烏司他丁(尿胰蛋白酶抑制劑，UTI)是一種來源于人尿的醣蛋白。作為一種蛋白酶抑制劑，它抑制胰蛋白酶、胰凝乳蛋白酶、乳酸鹽、脂肪酶、透明質酸酶和其他胰腺酶的活性。
烏司他丁是一種治療急性胰腺炎、慢性復發(fā)性胰腺炎，出血性、創(chuàng)傷性和內毒素性休克的有效藥物。
浩然生物可以供應以下規(guī)格的UTI原料。也可以根據客戶的需求準備其他規(guī)格的產品。
|
性狀 |
白色或類白色粉末 |
|
鑒別 |
符合規(guī)定 |
|
比活 |
不少于3500 IU/mg蛋白質 |
|
pH |
6.0-7.5 |
|
激肽釋放酶 |
及格 |
|
及格 |
不超過2% |
|
凝血質樣物質 |
及格 |
|
細菌內毒素 |
不超過1.25 EU/10,000 IU |
|
異常** |
陰性 45000 IU/0.5ml/鼠 |
|
干燥失重 |
不超過6% |
|
人類免疫缺陷病毒I型和II型抗原 |
陰性 |
|
乙肝病毒表面抗原 |
陰性 |
|
丙肝病毒抗體 |
陰性 |
This product is mainly used in the treatment of acute myocardial infarction, acute cerebral thrombosis, occlusion of cerebral blood vessel, peripheral arteriovenous thrombi, central retinal arteriovenous thrombi and other infarction diseases due to freshly formed clot
Haoran Biopharma can supply bulk UK with the following specifications. Products of various specifications can also be prepared according to customers' requests.
|
Appearance |
White or almost white, amorphous powder |
|
Identification |
Identified |
|
Activity |
Not less than 80,000 IU/mg |
|
Specific activity |
Not less than 120,000 IU/mg protein |
|
Clarity of solution |
Clear |
|
Thromboplastic contaminants |
Not less than 150 IU/ml |
|
HMW-Urokinase |
Not less than 90% |
|
Bacterial endotoxins |
Not more than 1.0 EU /10,000 IU |
|
Abnormal toxicity |
Negative at 5000 IU/0.5ml/mouse |
|
HIV I+II antibody |
Negative |
|
Hepatitis B surface antigen |
Negative |
|
HCV antibodies |
Negative |
